Across all studies, allocation of participants was by random assignment, and all but three studies [46, 56, 66] were double-blind. Study completion rates were low, with studies reporting the proportion of the sample who did not complete the protocol as 38.4% of the total randomised. Eighty-three percent of studies analysed their results by intention-to-treat, while five (12%) [33, 46, 53, 57, 61] were unclear in this regard and two (5%) [24, 45] did not. Females were underrepresented in the data, being only 29.7% of the total participants.
Pharmacological Treatment of Methamphetamine/Amphetamine Dependence: A Systematic Review
Depending on what type and the dosage of the prescribed amphetamine, take extended-release capsules once daily and immediate-release tablets and oral solutions up to three times per day. Schedule a time each day to take your amphetamines and stick to that schedule. People dependent on amphetamines become tired or sleepy—an effect that amphetamine addiction may last for 2 or 3 days after stopping the drug. Because some amphetamines are widely used as treatment for attention-deficit/hyperactivity disorder, obesity, and narcolepsy, there is a ready supply that can be diverted to illegal use. Some amphetamines are not approved for medical use and are manufactured and used illegally.
What dosage strengths does amphetamine come in?
This includes prescription and over-the-counter medicines, vitamins, and herbal products. Be sure your doctor knows if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson’s disease, migraine headaches, serious infections, or prevention of nausea and vomiting. These medicines may interact with amphetamine and dextroamphetamine and cause a serious condition called serotonin syndrome.
- Amphetamine’s isomers have long been known to be inhibitors of this important catabolising enzyme (Mantle et al., 1976; Miller et al., 1980; Robinson, 1985).
- Seventy-nine percent of the reviewed studies excluded participants with comorbid mental health diagnoses or concomitant medications prescribed for comorbid mental health diagnoses.
- Talk to your healthcare provider if you become dependent on any drug you are taking.
- Talk with your health care provider or see a mental health provider, such as a doctor who specializes in addiction medicine or addiction psychiatry, or a licensed alcohol and drug counselor.
- To our knowledge, no studies have investigated the effectiveness of pharmacological treatments concerning hard outcomes, such as hospitalization and death.
- Yes, amphetamines can pass into breast milk (chest milk) at low levels if parents follow the provider-prescribed dosage.
- This activity reviews the indications, action, and contraindications for amphetamine as an agent in treating ADHD and narcolepsy.
Amphetamine
The drug is typically made in clandestine laboratories with relatively inexpensive over-the-counter ingredients. Doctors can prescribe amphetamines to people living with ADHD, among other conditions. People may also use the drugs in an unprescribed manner, such as to stay awake for a study deadline or to suppress appetite.
International Patients
Immediate effects
Treatment / Management
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